Use of rabeprazole sodium and domperidone capsule.
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Question: Write detailed pharmacology and uses of rabeprazole sodium and domperidone capsule.
Asked By: Abhinav Sharma
College: Maharana Pratap engineering College
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Question: Write detailed pharmacology and uses of rabeprazole sodium and domperidone capsule.
Asked By: Abhinav Sharma
College: Maharana Pratap engineering College
1. Rabeprazole Sodium:
- Pharmacology:
- Rabeprazole is a proton pump inhibitor (PPI). It works by inhibiting the action of the proton pump in the gastric parietal cells. This pump is responsible for the final step in the secretion of gastric acid, making it a potent suppressor of gastric acid production. Rabeprazole selectively and irreversibly inhibits the hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cell. This inhibition leads to a decrease in both basal and stimulated gastric acid secretion.
- Uses:
- Gastroesophageal Reflux Disease (GERD): Rabeprazole is used to treat GERD, a condition where stomach acid flows back into the esophagus, causing symptoms such as heartburn and regurgitation.
- Pept…